5-MTHF (Active Folate)
5-Methyltetrahydrofolate
Bioactive form of folate bypassing MTHFR enzyme. Critical methyl donor for DNA synthesis and repair.
Typical longevity dose: 400-1000 mcg/day
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
Jarrow Methyl Folate 400mcg 0.4mg · capsule · 60 servings | Jarrow Formulas | $8.95 | $0.15 | 8 | Buy |
Pure Encapsulations Folate 1000mcg 1mg · capsule · 90 servings | Pure Encapsulations | $19.80 | $0.22 | 9 | Buy |
Thorne 5-MTHF 1mg 1mg · capsule · 60 servings | Thorne | $16.00 | $0.27 | 9 | Buy |
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Key Research
5-MTHF bypasses MTHFR polymorphisms affecting 40%+ of population.
Scaglione F, Panzavolta G (2014). Drugs
Interaction Warnings
Methotrexate
Folate may reduce methotrexate efficacy
Synergies
Vitamin B12
Works in concert in methionine cycle
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.