Alpha-Lipoic Acid
Alpha-Lipoic Acid (ALA / Thioctic acid)
Universal antioxidant soluble in both water and fat; regenerates vitamins C and E and glutathione; chelates heavy metals; improves insulin sensitivity by activating AMPK
Typical longevity dose: 300-600 mg/day
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
Nutricost Alpha Lipoic Acid 300mg 240 Capsules 300mg · capsule · 240 servings | iHerb | $10.00 | $0.04 | 8 | Buy |
NOW Foods Alpha Lipoic Acid 250mg 120 Capsules 250mg · capsule · 120 servings | iHerb | $12.23 | $0.10 | 8 | Buy |
NOW Foods Alpha Lipoic Acid 600mg 120 Capsules 600mg · capsule · 120 servings | iHerb | $17.13 | $0.14 | 8 | Buy |
Nutricost R-Alpha Lipoic Acid 100mg 120 Capsules 100mg · capsule · 120 servings | iHerb | $21.95 | $0.18 | 8 | Buy |
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Key Research
ALA is a mitochondrial compound that functions as antioxidant, metal chelator, and signaling molecule
Shay KP et al. (2009). Biochimica et Biophysica Acta
ALA improves insulin sensitivity and reduces oxidative stress markers in type 2 diabetes patients
Golbidi S et al. (2011). Current Diabetes Reviews
Interaction Warnings
Diabetes medications
ALA may lower blood sugar additively with insulin or oral hypoglycemics; monitor glucose
Thyroid medications
ALA may affect thyroid hormone levels; monitor if on levothyroxine
Synergies
Acetyl-L-Carnitine
ALA + ALCAR combination shown to improve mitochondrial function and reduce oxidative stress synergistically
Biotin
High-dose ALA may compete with biotin for transport; co-supplementation prevents deficiency
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.