B-Complex
Vitamin B Complex (B1, B2, B3, B5, B6, B7, B9, B12)
Water-soluble vitamin family essential for energy metabolism (B1, B2, B3, B5), neurotransmitter synthesis (B6, B12), DNA methylation and homocysteine metabolism (B9 folate, B12), and fatty acid synthesis; bioactive forms (methylfolate, methylcobalamin) preferred for MTHFR variants
Typical longevity dose: 1 capsule daily providing 25-100mg of each B vitamin (varies by formula)
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
NOW Foods B-50 Complex 100 Capsules mg · capsule · 100 servings | iHerb | $11.62 | $0.12 | 8 | Buy |
Life Extension BioActive Complete B-Complex 60 Capsules mg · capsule · 60 servings | iHerb | $8.10 | $0.13 | 8 | Buy |
Jarrow Formulas B-Right 100 Capsules mg · capsule · 100 servings | iHerb | $24.41 | $0.24 | 8 | Buy |
Thorne Basic B Complex 60 Capsules mg · capsule · 60 servings | iHerb | $27.00 | $0.45 | 8 | Buy |
Thorne Basic B Complex 60 Capsules mg · capsule · 60 servings | Thorne | $27.00 | $0.45 | 9 | Buy |
Add to cart: /cart?items=bcomplex-now-b50-100ct
Key Research
B vitamins are essential cofactors in virtually every cellular energy production pathway; deficiency causes fatigue, cognitive impairment, and mood disturbance
Kennedy DO (2016). Nutrients
B-vitamin supplementation reduced homocysteine levels by 25%, a key cardiovascular risk biomarker
Ford AH, Almeida OP (2012). American Journal of Clinical Nutrition
Interaction Warnings
Levodopa
Vitamin B6 can reduce levodopa's effectiveness in Parkinson's patients (unless taking carbidopa)
Metformin
Metformin depletes B12 over time; B-complex supplementation helps prevent this deficiency
Phenytoin
Folic acid may reduce phenytoin levels; phenytoin may reduce folate levels
Synergies
Magnesium
Magnesium is required to convert B vitamins to their active coenzyme forms; B6 in turn enhances magnesium absorption
Iron
B vitamins (especially B6, B9, B12) are essential for red blood cell formation alongside iron
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.