Melatonin
N-Acetyl-5-methoxytryptamine
Hormone produced by the pineal gland that regulates circadian rhythm. Also a potent antioxidant that accumulates in mitochondria. Production declines with age.
Typical longevity dose: 0.3-5 mg/day (lower doses often more effective)
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
NOW Melatonin 3mg 3mg · capsule · 180 servings | iHerb | $5.99 | $0.03 | 8 | Buy |
NOW Melatonin 3mg 3mg · capsule · 180 servings | NOW Foods | $6.99 | $0.04 | 7 | Buy |
Nutricost Melatonin 5mg 5mg · tablet · 240 servings | Nutricost | $8.95 | $0.04 | 6 | Buy |
Life Extension Melatonin 3mg 3mg · capsule · 60 servings | Life Extension | $6.75 | $0.11 | 9 | Buy |
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Key Research
Melatonin significantly reduced sleep onset latency and increased total sleep time.
Ferracioli-Oda E, et al. (2013). PLoS ONE
Interaction Warnings
Blood thinners
May increase bleeding risk
Diabetes medications
May affect blood sugar levels
Synergies
Magnesium
Both support sleep onset and quality
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.