Nicotinamide Riboside
Nicotinamide riboside chloride
NAD+ precursor converted via NR kinase pathway. Elevates NAD+, activating sirtuins (SIRT1, SIRT3) and PARPs for DNA repair.
Typical longevity dose: 300-1000 mg/day
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
Thorne NiaCel 300mg 300mg · capsule · 60 servings | Thorne | $46.00 | $0.77 | 9 | Buy |
Life Extension NAD+ Cell Regenerator 300mg 300mg · capsule · 30 servings | Life Extension | $34.50 | $1.15 | 9 | Buy |
TRU NIAGEN 300mg 300mg · capsule · 30 servings | Amazon⚠ | $40.00 | $1.33 | 2 | Buy |
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Key Research
NR 1000 mg/day effectively elevated NAD+ in healthy adults aged 55-79.
Martens CR, et al. (2018). Nature Communications
Interaction Warnings
Methyl donors
Consumes methyl groups — pair with TMG
Synergies
TMG
TMG provides methyl groups consumed during NR metabolism
Apigenin
Apigenin inhibits CD38 NAD+ degradation
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.