Phosphatidylserine
Phosphatidylserine (PS)
Phospholipid component of cell membranes critical for neuronal signaling; modulates cortisol response to stress, supports neurotransmitter production, and maintains membrane fluidity essential for synaptic function
Typical longevity dose: 100-300 mg/day
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
NOW Foods Phosphatidyl Serine 100mg 120 Capsules 100mg · capsule · 120 servings | iHerb | $22.65 | $0.19 | 8 | Buy |
Jarrow Formulas PS100 Phosphatidylserine 100mg 120 Capsules 100mg · capsule · 120 servings | iHerb | $37.98 | $0.32 | 8 | Buy |
Jarrow Formulas PS100 100mg 60 Softgels 100mg · softgel · 60 servings | iHerb | $20.42 | $0.34 | 8 | Buy |
Add to cart: /cart?items=ps-now-100mg-120ct
Key Research
FDA-qualified health claim: PS may reduce cognitive decline risk in elderly; shown to improve memory and processing speed
Glade MJ, Smith K (2015). Nutrition
300mg PS daily blunted cortisol response to physical stress in healthy men
Monteleone P et al. (2004). Neuroendocrinology
Interaction Warnings
Blood thinners
PS may have mild blood-thinning properties at high doses; use caution with anticoagulants
Anticholinergic drugs
PS supports acetylcholine function, potentially counteracting anticholinergic medications
Synergies
Omega-3 DHA
DHA is incorporated into PS in neuronal membranes; together they optimize brain membrane composition and fluidity
Bacopa monnieri
Both support cognitive function through complementary mechanisms - PS supports membranes while Bacopa modulates neurotransmitters
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.