Resveratrol
trans-Resveratrol
Activates SIRT1 and AMPK longevity pathways; mimics caloric restriction signaling; antioxidant and anti-inflammatory effects on cardiovascular endothelium
Typical longevity dose: 150-500 mg/day
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
NOW Foods Natural Resveratrol 200mg 120 Capsules 200mg · capsule · 120 servings | iHerb | $18.36 | $0.15 | 8 | Buy |
Doctor's Best Trans-Resveratrol 600mg 60 Capsules 600mg · capsule · 60 servings | iHerb | $17.99 | $0.30 | 8 | Buy |
ProHealth Longevity Trans-Resveratrol Plus 1000mg 60 Capsules 1000mg · capsule · 30 servings | iHerb | $27.97 | $0.93 | 8 | Buy |
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Key Research
Resveratrol activates SIRT1 deacetylase, modulating aging-related pathways including p53 and NF-kB
Berman AY et al. (2017). npj Precision Oncology
30-day resveratrol supplementation mimicked caloric restriction effects on energy metabolism in obese humans
Timmers S et al. (2011). Cell Metabolism
Interaction Warnings
Blood thinners (warfarin)
Resveratrol has antiplatelet properties that may potentiate anticoagulant effects
CYP3A4 substrates
Resveratrol may inhibit CYP3A4 enzyme, altering metabolism of certain drugs
Synergies
Quercetin
Quercetin inhibits resveratrol sulfation, improving its bioavailability and half-life
NMN/NR (NAD+ precursors)
Resveratrol activates sirtuins which require NAD+ as a substrate; pairing ensures adequate NAD+ supply
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.