Urolithin A
Urolithin A (6H-Dibenzo[b,d]pyran-6-one)
Activates mitophagy - the selective removal of damaged mitochondria; triggers PINK1/Parkin pathway to recycle dysfunctional mitochondria, improving cellular energy and muscle function
Typical longevity dose: 500-1000 mg/day
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
Timeline Mitopure Urolithin A 500mg 60 Softgels 500mg · softgel · 30 servings | Amazon⚠ | $125.00 | $4.17 | 2 | Buy |
Add to cart: /cart?items=urolithina-timeline-mitopure-500mg-60ct
Key Research
Urolithin A supplementation improved mitochondrial biomarkers in elderly humans after 4 weeks
Andreux PA et al. (2019). Nature Metabolism
1000mg urolithin A for 4 months increased muscle strength and endurance vs placebo in older adults
Liu S et al. (2022). JAMA Network Open
Interaction Warnings
No major known interactions
Urolithin A has been well-tolerated in clinical trials with no significant drug interactions reported
Synergies
CoQ10
Both support mitochondrial function through complementary mechanisms - UA recycles damaged mitochondria while CoQ10 supports electron transport
NAD+ precursors (NMN/NR)
Urolithin A improves mitochondrial quality while NAD+ precursors boost mitochondrial energy production
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.