methylationenergyneurological

Vitamin B12 (Methylcobalamin)

Methylcobalamin

Active form of B12 directly usable as a methyl donor. Essential for homocysteine metabolism and neurological function.

Typical longevity dose: 1000-5000 mcg/day

Price Comparison

ProductVendorPricePer ServingTrust

NOW Methyl B-12 5000mcg

5mcg · lozenge · 120 servings

Amazon$11.99$0.102Buy

NOW Methyl B-12 5000mcg

5mcg · lozenge · 120 servings

iHerb$13.99$0.128Buy

Jarrow Methyl B-12 5000mcg

5mcg · lozenge · 60 servings

Jarrow Formulas$13.95$0.238Buy

Thorne Methylcobalamin 1000mcg

1mcg · capsule · 60 servings

Thorne$14.00$0.239Buy

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Key Research

High-dose B vitamins slowed brain atrophy rate by 30% in elderly with mild cognitive impairment.

Smith AD, et al. (2010). PLoS ONE

Interaction Warnings

Metformin

Metformin reduces B12 absorption

Synergies

5-MTHF (Folate)

B12 and folate work together in methionine cycle

Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.