Vitamin E (Mixed Tocopherols)
Mixed Tocopherols (d-alpha, d-beta, d-gamma, d-delta tocopherols)
Fat-soluble antioxidant that protects cell membrane polyunsaturated fatty acids from lipid peroxidation; gamma-tocopherol specifically scavenges reactive nitrogen species (peroxynitrite); tocotrienols may inhibit HMG-CoA reductase
Typical longevity dose: 200-400 IU/day (mixed tocopherols preferred over alpha-only)
Price Comparison
| Product | Vendor | Price | Per Serving | Trust | |
|---|---|---|---|---|---|
NOW Foods Vitamin E-200 with Mixed Tocopherols 100 Softgels 134mg · softgel · 100 servings | iHerb | $8.71 | $0.09 | 8 | Buy |
NOW Foods Vitamin E-400 with Mixed Tocopherols 250 Softgels 268mg · softgel · 250 servings | iHerb | $30.61 | $0.12 | 8 | Buy |
Life Extension Gamma E Mixed Tocopherols & Tocotrienols 60 Softgels 230mg · softgel · 60 servings | iHerb | $27.00 | $0.45 | 8 | Buy |
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Key Research
Gamma-tocopherol uniquely traps nitrogen-based free radicals; mixed tocopherols superior to alpha-tocopherol alone
Jiang Q (2014). Free Radical Biology and Medicine
Vitamin E enhances T-cell function and reduces infection risk in elderly populations
Lee GY, Han SN (2018). Nutrients
Interaction Warnings
Blood thinners (warfarin)
Vitamin E has antiplatelet activity; high doses (>400 IU) may increase bleeding risk with anticoagulants
Statins
Some evidence that high-dose vitamin E may slightly reduce the HDL-raising effect of statin/niacin combinations
Chemotherapy/radiation
Antioxidant effects may protect cancer cells from oxidative damage therapies; consult oncologist
Synergies
Vitamin C
Vitamin C regenerates oxidized vitamin E back to its active form, extending its antioxidant lifespan
Selenium
Selenium is cofactor for glutathione peroxidase; works synergistically with vitamin E in antioxidant defense
CoQ10
Both are lipid-soluble antioxidants that protect mitochondrial and cell membranes
Disclaimer: This information is for educational purposes only and is not medical advice. Research citations are provided for reference — consult your healthcare provider before starting any supplement regimen. Prices are estimates and may not reflect current retail pricing.